Immunology: Genetics
Horizontal Gene Transfer: Genes hopping between species
Horizontal Gene Transfer is the process whereby genes from different organisms blend together to create wholly new forms of life. It has been studied mostly in microorganisms but has been found to occur when we eat food and even between living humans.
We can't help wondering what happens when we combine three to thirteen known viruses in one injection with an uncountable number of unknown, undetected strains of viral and bacterial dna and then give half a dozen of these injections at once.
It has been hypothesized that the H1N1 virus that wiped out 4% of the world's population in 1918 and 1919 was created through horizontal gene transfer between the dozens of experimental vaccines given to American troops. The pandemic was traced back to a military staging base in Kansas, from where it began in January and spread via troop movement routes to the rest of the world.
Many of the deaths were attributed to a combination of the filth of the trenches, the malnourishment among the soldiers and a "cytokine storm" in which the immune systems kicked up a storm of epic proportions. It is well documented that the immune system tilts out of balance towards cytokine production in the wake of vaccination. And it is well documented that many of the victims never saw battle, never even left the country and, once the battery of vaccines was made available to the public, had never even been soldiers.
Click here to read the wikipedia page on horizontal gene transfer.
We can't help wondering what happens when we combine three to thirteen known viruses in one injection with an uncountable number of unknown, undetected strains of viral and bacterial dna and then give half a dozen of these injections at once.
It has been hypothesized that the H1N1 virus that wiped out 4% of the world's population in 1918 and 1919 was created through horizontal gene transfer between the dozens of experimental vaccines given to American troops. The pandemic was traced back to a military staging base in Kansas, from where it began in January and spread via troop movement routes to the rest of the world.
Many of the deaths were attributed to a combination of the filth of the trenches, the malnourishment among the soldiers and a "cytokine storm" in which the immune systems kicked up a storm of epic proportions. It is well documented that the immune system tilts out of balance towards cytokine production in the wake of vaccination. And it is well documented that many of the victims never saw battle, never even left the country and, once the battery of vaccines was made available to the public, had never even been soldiers.
Click here to read the wikipedia page on horizontal gene transfer.
Engineered Genes Spreading Through the Environment, Infecting Others
"A culture of denial over the horizontal spread of genetically modified nucleic acids prevails in the face of direct evidence that it has occurred widely when appropriate methods and molecular probes are used for detection."
Click here to read the review of the literature published in 2014.
Click here for a facebook page with a list of forty four published studies showing gmos to be dangerous.
Click here to read the review of the literature published in 2014.
Click here for a facebook page with a list of forty four published studies showing gmos to be dangerous.
Transgenerational epigenetic inheritance
"The experiences of a parent, even before conceiving, markedly influence both structure and function in the nervous system of subsequent generations," the report concluded
Behaviour can be affected by events in previous generations which have been passed on through a form of genetic memory.
Experiments showed that a traumatic event could affect the DNA in sperm and alter the brains and behaviour of subsequent generations.
"There is absolutely no doubt that what happens to the sperm and egg will affect subsequent generations."
Click here to read the article in "The Guardian" from December, 2013.
"Our findings provide a framework for addressing how environmental information may be inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels." So conclude the researchers in their study, published in December, 2013 in the journal, "Nature Neuroscience."
Click here to read an abstract of their study, view some of their data and access their 54 scientific sources.
Behaviour can be affected by events in previous generations which have been passed on through a form of genetic memory.
Experiments showed that a traumatic event could affect the DNA in sperm and alter the brains and behaviour of subsequent generations.
"There is absolutely no doubt that what happens to the sperm and egg will affect subsequent generations."
Click here to read the article in "The Guardian" from December, 2013.
"Our findings provide a framework for addressing how environmental information may be inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels." So conclude the researchers in their study, published in December, 2013 in the journal, "Nature Neuroscience."
Click here to read an abstract of their study, view some of their data and access their 54 scientific sources.
Epigenetic Findings in Autism
"These alterations in gene expression, obtained through DNA methylation and/or histone modifications, result from transcriptional regulatory influences of environmental factors, such as nutritional deficiencies, various toxicants, immunological effects, and pharmaceuticals."
So find a group of Italian researchers in regards to autism.
Click here to read their entire review of epigenetic factors in autism in this paper published in September, 2013 in the "International Journal of Environmental Research and Public Health."
So find a group of Italian researchers in regards to autism.
Click here to read their entire review of epigenetic factors in autism in this paper published in September, 2013 in the "International Journal of Environmental Research and Public Health."
Harvard Identifies over 600 Genes Disrupted by Environmental Factors in Autism
There are over six hundred fifty genes that have been found to be affected in autism.
That is not a genetic disease. That is the result of environmental factors disrupting gene replication.
"A group of Massachusetts General Hospital (MGH) investigators has identified key underlying biological processes that involve some of the hundreds of genes known to contribute to the risk of autism spectrum disorders
'Our pathway network analysis is the first bioinformatics study in autism to connect the dots of brain and body – of autism and accompanying medical conditions, of autism and vulnerability to environmental stress – in one investigation,'"
Click here to read a press release from Massachusetts General Hospital discussing the issue.
That is not a genetic disease. That is the result of environmental factors disrupting gene replication.
"A group of Massachusetts General Hospital (MGH) investigators has identified key underlying biological processes that involve some of the hundreds of genes known to contribute to the risk of autism spectrum disorders
'Our pathway network analysis is the first bioinformatics study in autism to connect the dots of brain and body – of autism and accompanying medical conditions, of autism and vulnerability to environmental stress – in one investigation,'"
Click here to read a press release from Massachusetts General Hospital discussing the issue.
Genetic Analysis Shows Autism Related to Immune and Nervous System Disorder
"Recent studies of genomic variation associated with autism have suggested the existence of extreme heterogeneity. Large-scale transcriptomics should complement these results to identify core molecular pathways underlying autism. Here we report results from a large-scale RNA sequencing effort, utilizing region-matched autism and control brains to identify neuronal and microglial genes robustly dysregulated in autism cortical brain. Remarkably, we note that a gene expression module corresponding to M2-activation states in microglia is negatively correlated with a differentially expressed neuronal module, implicating dysregulated microglial responses in concert with altered neuronal activity-dependent genes in autism brains. These observations provide pathways and candidate genes that highlight the interplay between innate immunity and neuronal activity in the aetiology of autism."
http://www.nature.com/ncomms/2014/141210/ncomms6748/full/ncomms6748.html#affil-auth
http://www.nature.com/ncomms/2014/141210/ncomms6748/full/ncomms6748.html#affil-auth
Common genotype found in vaccinated autistic children: MTHFR
Many autistic kids have unusual profiles of this gene. Related metabolic differences are discussed at length in the article. Of particular note regarding autism and other manifestations of brain damage is the decreased ability to filter metals from the body.
Current group think calls these mutations and believes them to be problematic. At Outlaw Health we remain unconvinced. Estimates are that fifty to seventy percent of the population has the most common form of this gene while thirty to fifty percent have variations.
It seems likely to us that these variations provide some as yet unrecognized benefit. It seems unlikely to us that thirty or more percent of people would have negative mutations that provided no benefit.
Click here to read a detailed account of the MTHFR gene, recently found to be relevant in many ways to our health.
Current group think calls these mutations and believes them to be problematic. At Outlaw Health we remain unconvinced. Estimates are that fifty to seventy percent of the population has the most common form of this gene while thirty to fifty percent have variations.
It seems likely to us that these variations provide some as yet unrecognized benefit. It seems unlikely to us that thirty or more percent of people would have negative mutations that provided no benefit.
Click here to read a detailed account of the MTHFR gene, recently found to be relevant in many ways to our health.
MTHFR Gene Identified in Small Pox Vaccine Reactions
"Genetic polymorphisms in an enzyme previously associated with adverse reactions to a variety of pharmacologic agents (MTHFR) and an immunological transcription factor (IRF1) were associated with AEs after smallpox vaccination in two independent study samples. These findings highlight common genetic variants with promising clinical significance that merit further investigation."
So found a team of researchers from Vanderbilt, Dartmouth, the NIH and others.
Click here to read the abstract of their findings published in 2008 in the "Journal of Infectious Diseases."
So found a team of researchers from Vanderbilt, Dartmouth, the NIH and others.
Click here to read the abstract of their findings published in 2008 in the "Journal of Infectious Diseases."
Retroviruses Found in Vaccines Could Be Permanently Mutating Human Genes
The Washington Post reports on retroviruses from chickens found in the mmr vaccine. While the news report hedges carefully about the perceived safety of the vaccine by the vaccine manufacturers, we know that cross species contamination by retroviruses can be very dangerous.
Click here to read the Washington Post article from 1995.
This NIH researcher found that all vaccines are contaminated with retroviruses.
Click here to watch this hour long video on youtube in which she discusses her findings.
Click here to read the Washington Post article from 1995.
This NIH researcher found that all vaccines are contaminated with retroviruses.
Click here to watch this hour long video on youtube in which she discusses her findings.
Animal Retroviruses and Genetic Mutations Found in Vaccines
"Mutations and minority variants, relative to vaccine strains, not known to affect attenuation were detected in OPV, mumps virus, and varicella-zoster virus. The anticipated detection of endogenous retroviral sequences from the producer avian and primate cells was confirmed. Avian leukosis virus (ALV), previously shown to be noninfectious for humans, was present as RNA in viral particles, while simian retrovirus (SRV) was present as genetically defective DNA. Rotarix, an orally administered rotavirus vaccine, contained porcine circovirus-1 (PCV1), a highly prevalent nonpathogenic pig virus, which has not been shown to be infectious in humans. Hybridization of vaccine nucleic acids to a panmicrobial microarray confirmed the presence of endogenous retroviral and PCV1 nucleic acids."
The authors go out of their way to make unsupported statements about the safety and effectiveness of vaccines while demonstrating that genetic recombination of viruses is occurring in vaccines and we do not know the effects of these processes. They also demonstrate that animal retroviruses are commonly found in vaccines. One common retrovirus thought to have originated in animals and then passed to humans is HIV. These sorts of viruses and viral fragments are also thought to play a role in cancer.
Click here to read the paper published in 2010 in the "Journal of Virology." We suggest reading the data and ignoring the pandering.
The authors go out of their way to make unsupported statements about the safety and effectiveness of vaccines while demonstrating that genetic recombination of viruses is occurring in vaccines and we do not know the effects of these processes. They also demonstrate that animal retroviruses are commonly found in vaccines. One common retrovirus thought to have originated in animals and then passed to humans is HIV. These sorts of viruses and viral fragments are also thought to play a role in cancer.
Click here to read the paper published in 2010 in the "Journal of Virology." We suggest reading the data and ignoring the pandering.
Viruses May Be Evolving to Cause Cancer In Response to Vaccines
"Here, we present and theoretically validate a mechanism by which the vaccine alters the transmission–recovery trade-off that constrains HPV's virulence such that higher oncogene expression is favoured. With a high oncogene expression strategy, the virus is able to increase its viral load and infected cell population before clearance by the vaccine, thus improving its chances of transmission.
We also discuss the importance of better quantifying the duration of challenge infections and the degree to which a vaccinated host can shed virus. The generality of the models presented here suggests a wider applicability of this mechanism, and thus highlights the need to investigate viral oncogenicity from an evolutionary perspective."
Click here to read this study from Canadian researchers published in January, 2015.
We also discuss the importance of better quantifying the duration of challenge infections and the degree to which a vaccinated host can shed virus. The generality of the models presented here suggests a wider applicability of this mechanism, and thus highlights the need to investigate viral oncogenicity from an evolutionary perspective."
Click here to read this study from Canadian researchers published in January, 2015.
Vaccine Manufacture Causes Viral Mutation
"Applied evolution, in the form of serial passage in novel host cells, is a “classical” method to generate live-attenuated viruses (for vaccines).
However many live-attenuated vaccines exhibit reversion to virulence through back-mutation of attenuating mutations, compensatory mutations elsewhere in the genome, recombination or reassortment, or changes in quasispecies diversity.
Additionally the combination of multiple live-attenuated strains may result in competition or facilitation between individual vaccine viruses, resulting in undesirable increases in virulence or decreases in immunogenicity."
Click here to read this study out of New Mexico State University published in 2012 in the journal, "Evolution."
However many live-attenuated vaccines exhibit reversion to virulence through back-mutation of attenuating mutations, compensatory mutations elsewhere in the genome, recombination or reassortment, or changes in quasispecies diversity.
Additionally the combination of multiple live-attenuated strains may result in competition or facilitation between individual vaccine viruses, resulting in undesirable increases in virulence or decreases in immunogenicity."
Click here to read this study out of New Mexico State University published in 2012 in the journal, "Evolution."
Agricultural Pests Out Evolving Genetically Modified Crops and Pesticides
"With bollworm developing resistance to Bt cotton crop, the government has decided to promote cultivation of indigenous varieties of the crop in a big way this year.
In 2015-16 crop year (July-June), there was a significant damage to cotton crop because of whitefly and pink bollworm pest attack in states like Haryana, Punjab, Rajashtan, Gujarat and Andhra Pradesh."
India is reverting back to native cotton from the gm variety.
Click here to read the entire article from the "Economic Times of India" from April, 2016.
In 2015-16 crop year (July-June), there was a significant damage to cotton crop because of whitefly and pink bollworm pest attack in states like Haryana, Punjab, Rajashtan, Gujarat and Andhra Pradesh."
India is reverting back to native cotton from the gm variety.
Click here to read the entire article from the "Economic Times of India" from April, 2016.